Evolysse (TM)

Evolysse HA filler alternative made with Cold-X™ Technology is designed to preserve the natural HA structure.

Evolysse™ is the next-generation injectable hyaluronic acid made with Cold-X Technology by Symatese. The Evolysse collection launches with two injectable HA gels (‘Smooth’, and ‘Form’), each with unique viscoelastic properties, to soften wrinkles that form in dynamic areas of the face, such as the nasolabial folds.

Developed by global hyaluronic acid expert

Cold-X Technology was studied, developed and enhanced by industry leader Symatese, renowned for its scientific expertise in the skin and introducing many of the leading technologies used in medical aesthetics today. Symatese is a well-established leader in the industry, having pioneered the development of the latest generation of Restylane^® products in the U.S., incorporating cutting-edge XpresHAn Technology™ and OBT^®. In addition, the company is actively engaged in advanced research programs focused on tissue regeneration, particularly in the skin, in collaboration with L’Oréal.

Evolus evaluated multiple hyaluronic acid technologies, seeking the most innovative technology provider before entering into a licensing agreement with Symatese in 2023.

Cold-X Technology

Temperature Matters. Cold-X Technology utilizes near-freezing temperatures intended to preserve the natural HA structure for a more natural look.

This novel approach with Cold-X Technology results in HA products that perform in the treatment area
and are designed to feel natural in the facial tissue.

Evolysse HA filler alternative is the only treatment made with Cold-X Technology.

A majority of people in Evolysse clinical studies were satisfied after treatment and reported. Smile and laugh lines look better smiling ànd when relaxed. Subjects felt better about the appearance of their smile and laugh lines. Results lasted 12 months. They would recommend this treatment to a friend.

The most common side effects are temporary at the injection site, such as tenderness, swelling, bruising, pain, redness, and lumps.

Understanding Evolysse HA Filler Alternative

Hyaluronic acid (HA) is a naturally occurring substance that provides skin hydration to help maintain flexibility and elasticity.

HA is a key ingredient in dermal fillers because it adds volume that smoothens facial wrinkles.

Evolysse is made from a modified form of the HA that is naturally found in your body.

Cold-X long chain HA

Click here for a more elaborate overview of our available treatment options.